Diclofenac and alcohol - are they compatible?

introduction

Pain can be bothersome and protracted. Relief is often promised by pain killers that target different mechanisms of action and application. These so-called analgesics (Painkillers) also includes the drug diclofenac. Diclofenac is called Non-opioid analgesics classified and is used for mild to moderate pain.

Another area of ​​application of Diclofenac are Inflammation which among other things rheumatism occur.

However, it is predominantly at Sports injuries such as Strains or Bruises second hand.

In addition to its pain-relieving effect, Diclofenac also has one antipyretic (antipyretic) and anti-inflammatory (anti-inflammatory) component.

Diclofenac and alcohol

Diclofenac is a drug of potentially liver damaging can be. If you combine Diclofenac with other potentially liver-damaging substances, such as alcohol, there may be an increased effect of the Side effects and Interactions come.

Diclofenac in combination with alcohol increases side effects such as:

• fatigue
• nausea
• Vomit
• Indigestion
• a headache
• Loss of appetite
• Rashes

In addition, the risk is a Gastric ulcer to develop increases and with it also Bleeding in the stomach. Also in further sections of the gastrointestinal tract bleeding may occur.

At Alcohol abuse Not only can liver damage occur more frequently as a result of taking diclofenac, but also liver damage Renal dysfunction, one increased tendency to bleed as well as a increased blood pressure.

In combination with alcohol there are particularly noticeable side effects such as fatigue, dizziness and delayed responsiveness on. Here you should note that you are under the influence of alcohol not able to drive are and no machines should serve.

Generally it should be said that it is not recommended will combine alcohol and diclofenac as it is too severe liver damage and internal bleeding can lead. Besides, that is Reduced responsivenesswhich can also lead to dangerous situations.

Other interactions

In general, as with any other drug, Diclofenac Interactions with other drugs occur.

You should be particularly careful here elderly patients be who are already weakened or under one Long-term medication with other drugs stand. With them it can come more often to unwanted side effects, among other things gastrointestinal bleeding could be.

There can also be interactions during pregnancy come. Diclofenac tablets should therefore be taken during pregnancy always discussed with the doctor become. This is especially true in the first trimester and second trimester of pregnancy.

During the Lactation it is not recommended to take diclofenac, as this cannot be ruled out Diclofenac breakdown products in the Breast milk are located.

Especially at higher-dose diclofenac tablets can the Ability to drive and the Use of machines restricted be. Due to rare side effects such as fatigue or dizziness the safe operation of machines or safety in road traffic can no longer be guaranteed.

In Combination with other drugs can diclofenac be a Increase their effect trigger. If you are taking other medications, always ask your doctor for advice. In combination with Corticosteroids can it to one Increased risk of gastrointestinal ulcers and Bleeding in the gastrointestinal tract come.

Diclofenac can do the Effects of antihypertensive drugs such as Attenuate ACE inhibitors. It can also occur with simultaneous intake of diclofenac and antihypertensive agents as well diuretic drugs to a Renal dysfunction come. When taken at the same time with potassium-sparing diuretics, a Control of potassium levels recommended as it can lead to an increased concentration of potassium in the blood.

At Antidiabetic drugs is also recommended when taking Diclofenac tablets on one Control of blood sugar levels to pay attention.

Mechanism of action

The Effect of Diclofenac is based on an inhibition (Inhibition) of the Cyclooxygenases COX-1 and COX-2. Cyclooxygenases are responsible for that Regulation of inflammation. They express as Enzymes Fabrics like that Prostaglandin. Prostaglandin is a Tissue hormone which for pain, inflammation and Blood clotting responsible is. Through the not selective Diclofenac unfolds its inhibition of cyclooxygenases pain reliever and anti-inflammatory effect.

Of the Active ingredient diclofenac is available in many different commercial products. They include, among others Voltaren but also:

• Diclo
• Diclofen
• Allyorane
• Arthrex Diclac
• Diclophlogont
• Dolgit Diclo
• Duravolten
• Effekton
• Flector
• Jenaphenac
• Jutafenac
• Monoflam
• Myogite
• Rewodina
• Sandoz pain gel
• Sigafenac
• Solaraze
• ...

Dosage forms of Diclofenac

Of the Active ingredient diclofenac is in different designs and dosage forms available in the stores. Diclofenac can be used as a tablet or capsule be taken. It is also called ointment, gel or band Aid sold. Suppositories, drops or Injection solutions with the active ingredient diclofenac are also available. All versions of the Diclofenac are pharmacy only and also subject to prescription depending on the amount of active ingredient.

application

The Use of Diclofenac is depending on the version purchased:

• Diclofenac gel or ointment serves the external application. The gel or ointment is applied thinly to the affected area and carefully rubbed in. A Association should be created, however not airtight be. Wait a few minutes before applying a bandage until the gel or ointment dries up slightly. Diclofenac gel or ointment can 3 times a day be applied.
• Diclofenac tablets are in different designs to obtain. these can 25mg, 50mg, and 150 mg of the active ingredient contain: Diclofenac 25mg should be taken with a sip of water one to two hours before a meal. Children aged 15 and over and adults take daily 1 to 2 tablets 2-3 times a. This corresponds to a daily dose of 50 mg to 150 mg. The The maximum daily dose for Diclofenac tablets is 150 mg. This must be taken into account when taking. So we took a 150 mg diclofenac tablet only once a day. On the other hand, a tablet with 50 mg of active ingredient can be taken 3 times a day.
• Diclofenac suppositories contain 100 mg of active ingredient and will once a day introduced. If possible, the suppository should be inserted deep into the anus after a bowel movement.