Side effects of Celebrex


The active ingredient in Celebrex® is celecoxib. Celebrex® is a non-steroidal anti-inflammatory drug (NSAID) intended to combat irritation and pain associated with degenerative joint diseases.

However, Celebrex® also causes undesirable effects. The spectrum of side effects is very wide. The side effects do not occur to the same extent in every patient who is treated with Celebrex®. Every body is individual and reacts differently to taking Celebrex®.
In addition, the degree to which the side effects show up also depends on whether the drug was given as an injection, tablet, solution, or ointment.

Water retention

Often patients complain that Celebrex® have taken over Edema. Edema is fluid retention in the tissue.

Digestive tract

Often can through Celebrex® the hydrochloric acid secretion in the stomach, which is of central importance for the breakdown of food proteins, may be reduced.
Also the Inhibition of gastric emptying is known to be a possible side effect of Celebrex®. When taking Celebrex orally, with Inflammation of the mouth or stomach lining be expected.

In addition, it can lead to a spastic increase in the tone of the circular muscles in the large and small intestine. In this case, the transport of the food pulp is disrupted or completely stopped. The inhibition of gastrointestinal tract activity possibly caused by Celebrex® can ultimately lead to constipation, diarrhea, Gas, nausea and Vomit lead and be very painful.

Very seldom also arise from treatment with Celebrex® Ulcers all in one Gastrointestinal tract.

Treatment with Celebrex® is not recommended if the patient is under Gastrointestinal bleeding, Stomach ulcer, Crohn's disease or other gastrointestinal diseases.

immune system

Celebrex® has an impact on that immune system. On the one hand, Celebrex® can lead to numerous inflammations of various organs, such as the Pancreas, Sinuses, Respiratory and urinary tract.
While this happens more often with the airways and sinuses, inflammation of the other organs mentioned is less common.

Second, as a side effect allergic reaction occur. These are initiated by the release of histamine from Celecoxib (active ingredient in Celebrex®).
histamine plays a very important role in allergic processes. These can turn out to be Rashes, itching or Redness manifest on the skin.


Celebrex® can both raise and lower blood pressure, although the former side effect is rare. If the blood pressure drops too much, it can be life-threatening in extreme cases Circulatory shock.
Other side effects that are known in the cardiovascular system are Heart attack and Heart failure. Therefore, the Celebrex® administration to patients with severe, decompensated Heart failure contraindicated.

Psychological complaints

As undesirable effects of Celebrex® are sleepiness, but also sleep disorders, a headache and Poor concentration known. In rare cases, Celebrex® callsAnxiety, depression, confusion and Delusions emerged.

Blood count

Sometimes it comes to one anemia, so a lack of red blood cells (erythrocytes). Therefore, when taking Celebrex®, symptoms of anemia such as paleness, tiredness, and reduced physical and mental performance occasionally occur.

The number of white blood cells (leukocytes) and platelets decreased by Celebrex®. Because white blood cells maintain the immune system, the risk of infection can be increased if there is a lack of white blood cells. Absence Platelets (Platelets) called, one speaks of one Thrombocytopenia. This is associated with blood clotting disorders.


Celebrex® can in rare cases the Bronchi narrow, causing shortness of breath. to cough also occurs as a side effect. Furthermore, Celebrex® therapy can lead to a Respiratory infection come.


Very rarely do Celebrex® patients See- and Taste disorders, Photosensitivity and a reduction of the Hearing performance.

Occasionally come tingling, partially painful Paresthesia without added charm. In this case one speaks of Paresthesia. Likewise can Numbness occur.

Other side effects

Other common side effects are Impaired liver function and dizziness.
In very few cases, when taking Celebrex®, the following occur:

  • Strokes
  • epilepsy
  • Hair loss
  • Skin pigmentation disorders
  • Meningitis
  • Vascular disease
  • Menstrual disorders and
  • Kidney failure