Proff® pain cream


Proff® pain cream is a cream for the external treatment of various muscle and joint diseases.
The cream has a pain-relieving effect and supports the therapy of osteoarthritis, swelling, inflammation and sports and accident injuries.

The cream is applied several times a day and gently rubbed in. Proff® pain cream is also suitable for applying ointment bandages.

Indications for the Proff® pain cream

The Proff® pain cream is used for various diseases and injuries.
This includes:

  • degenerative joint diseases that are accompanied by pain;
  • Osteoarthritis or rheumatic diseases of the joints and spine;
  • the so-called muscle rheumatism, the most common form of which is fibromyalgia. It manifests itself in severe muscle pain and restricted mobility;
  • Inflammation or swelling of other soft tissues such as bursa, tendons, ligaments and joint capsules, proff® pain cream can also be used;
  • Sports injuries and accidental injuries such as bruises, sprains or strains.

Read more on the subject below: Arthrosis

Proff® pain cream for osteoarthritis

Osteoarthritis is a joint disease that is very common in old age and is associated with severe pain, swollen joints and restricted mobility.

Usually smaller joints of the fingers and hands, knees or hips are affected, but in general every joint can show osteoarthritis.

The destruction of the cartilage layer slowly leads to chronic inflammation of the joints with pain and swelling. Proff® pain cream is suitable for use in osteoarthritis and has a pain-relieving and anti-inflammatory effect thanks to the active ingredient ibuprofen.

Are you interested in treatment options for osteoarthritis? Then read our next article below: Therapy of osteoarthritis


As the name suggests, Proff® pain cream contains the active ingredient ibuprofen in an oil / water emulsion.
Ibuprofen is a drug from the group of non-steroidal anti-inflammatory drugs (NSAIDs).

It has analgesic and anti-inflammatory effects and is also used in tablet form to treat fever. When used on the skin, it is absorbed into the organism to a much lesser extent, but acts primarily below the application site.

Proff® pain cream is alcohol-free and skin-friendly, and its oil content also protects the skin from drying out.

In addition, proff® pain cream contains the preservative ethyl 4-hydroxybenzoate sodium and propylene glycol. If you are known to be hypersensitive to the active ingredient or the other ingredients, proff® pain cream must not be used.

Read more on the subject below: NSAIDs


Ibuprofen is a drug from the group of pain relievers and anti-inflammatory drugs.
By inhibiting enzymes that release inflammation-mediating tissue hormones (so-called prostaglandins), ibuprofen inhibits inflammation, has an analgesic and fever-lowering effect.

When taken orally, ibuprofen affects the lining of the stomach and can damage it. The theory behind the use as a cream is a locally increased intake, which is associated with fewer systemic side effects, such as an increased risk of gastrointestinal bleeding. The concentration of the active ingredient is increased at the application site, which unfolds the effect on inflamed or swollen joints. proff® pain cream has a targeted analgesic and anti-inflammatory effect and is well tolerated by the skin for rheumatism, osteoarthritis and muscle and joint problems.

Read more on the subject below: Prostaglandins


The cream is used three to four times a day.
Depending on the affected joint or painful area, a strand of cream a few centimeters long should be applied, which corresponds to between 2 and 5 g of cream.

Proff® pain cream is rubbed in lightly. In the event of bruises and sprains, an ointment bandage with proff® pain cream can be applied.

The cream is usually used for between two and three weeks.

Side effects

When using proff® pain cream, local skin reactions can often occur, which can be accompanied by redness, itching, burning or rashes.

Hypersensitivity reactions such as rashes are possible, and narrowing of the airways can occur very rarely.

Side effects on organ systems that occur with the systemic use of ibuprofen cannot be ruled out if proff® pain cream is applied over a large area and over a longer period of time.

However, the rate of absorption through the skin is very low at around 5%.

Propylene glycol, which is also one of the ingredients, can cause skin irritation.


So far, no interactions between the local application of proff® pain cream and other drugs are known.

Proff® pain cream should always be applied to healthy, uninjured skin.

Is that compatible with alcohol?

So far there is no evidence of an interaction between proff® pain cream and alcohol consumption.

The active ingredient ibuprofen only has a minor systemic effect, so no interactions are to be expected with correct use and moderate alcohol consumption.

The next article could also be of interest to you: Effect of alcohol - influence on the various organs

Can it be used during breastfeeding and pregnancy?

There is insufficient experience with the use in the first two thirds of pregnancy, pregnant women should use the cream after careful consideration.

According to the package insert, proff® pain cream is contraindicated in the last trimester of pregnancy, as the active ingredient ibuprofen could cause side effects.

Accordingly, the inhibition of labor, a prolongation of pregnancy and childbirth, as well as toxic effects on the cardiovascular system and kidneys of the child are potential side effects.

In addition, ibuprofen increases the bleeding tendency in mother and child. Small amounts of ibuprofen pass into breast milk. So far, no adverse consequences for the infant have been known, and breastfeeding does not usually have to be interrupted if it is used for a short time.

Breastfeeding mothers should not use proff® pain cream in the breast area and avoid direct contact of the child with the cream.

Read more on the subject below: Medicines in pregnancy


  • Proff® pain cream may not be used if there is hypersensitivity to the active ingredient ibuprofen and other ingredients of the cream.
  • If you are allergic to other non-steroidal anti-inflammatory drugs, i.e. painkillers or rheumatoid drugs, proff® pain cream should not be used.
  • Proff® Pain Cream is only suitable for use on the skin and must not be applied to open injuries or mucous membranes.
  • proff® pain cream must not be used in the last third of pregnancy; its mode of action could interfere with the birth process and threatening side effects in the child and mother.
  • Patients who suffer from asthma or respiratory diseases can suffer so-called analgesic asthma attacks or local swellings when using proff® pain cream and may only use the drug as prescribed and under supervision.

Read more on the subject below: Ibuprofen in pregnancy

How much does a Proff® pain cream cost?

Proff® pain cream is available in different pack sizes from different suppliers.

It can be purchased at the pharmacy without a prescription.

Proff® Pain Cream 5% is available in a 100g pack for around 8 €.