Cefuroxime in pregnancy

introduction

Cefuroxime is an antibiotic from the group of cephalosporins.
Like all antibiotics, cephalosporins are harmful to bacteria. Cefuroxime does this by preventing growing bacteria from building their cell wall. This causes them to "burst" due to their internal pressure.

Cefuroxime can either be in a vein injected or as a tablet orally be taken. The cefuroxime to be taken as a tablet is called “Cefuroxim-Axetil” because it contains a chemical tag that enables it to be absorbed through the intestines. However, it works just like regular cefuroxime. Typically be 2 x 0.5 g a day taken. Oral treatment is used in particular bacterial respiratory infections, of the Almonds, of Throat, of Middle ear, of the Sinuses just like Urinary tract infections, of the Breasts and the skin used if the bacteria are sensitive to this antibiotic. This is through that wide spectrum of activity of cefuroxime is often the case.

Venous administered cefuroxime is also used for infections of various organs, for example one lung infection, used. Usually this will be 1.5 g 3 times a day administered.

In contrast to many other antibiotics, cefuroxime can use the so-called "Blood-brain barrierovercome and so also fight bacteria in the brain.

Cefuroxime during pregnancy and breastfeeding

Cefuroxime is generally a remedy that is often and gladly used by pregnant women: it belongs to several diseases during the pregnancy to the Antibiotics of the "1st Choice“- that means that in these cases there are no better alternatives.
These diseases include e.g. Infections of the -

  • urethra
  • bladder
  • kidney and
  • Breasts

The oral administration of medication is used during the pregnancy generally preferred. Therefore, cefuroxime is only used at severe or. dangerous infections, for example with infections of the kidneys or the renal pelvis, venous administered. Since studies on the effectiveness of drugs in pregnant women cannot be carried out because of the risk to the child, the choice of antibiotic for infections during pregnancy is based on Empirical values. Cefuroxime is one of those drugs with which one has a lot of experience. It has been found that the child is neither in the early organ formation phase nor in the later growth phase of the pregnancy by Cefuroxime is harmed. According to today's knowledge, it is therefore called not teratogenic (= "Does not cause malformations") and not foetotoxic (= “Not harmful to the child”). If taken correctly, it is safe for the child. Nevertheless, before each use during pregnancy it should be checked whether the drug is necessary in order to avoid possibly overlooked risks.

During the Lactation heard Cefuroxime also to one 1st choice antibioticbecause it's only in smallest amounts in the Breast milk crosses over and therefore hardly gets into the child's circulation. In rare cases it can still occur in infants Diarrhea cause.

Can you take cefuroxime if you want to get pregnant?

Cefuroxime does not affect fertility and can therefore also be used if you want to get pregnant. Farther leads it not to damage the implantation pregnancy.

What happens if you get pregnant while taking cefuroxime?

If you pregnant while taking cefuroxime you have to at first don't worry to make the pregnancy intact.

in the first trimester of pregnancy must the Ingestion however strictly weighed become. Therefore you should attending physician the notify existing pregnancyso that he or she can discuss with the pregnant woman whether she needs to continue taking cefuroxime or not. Possibly will that Discontinued medication or switched to another. However, therapy with cefuroxime can also be continued if necessary.

dosage

Cefuroxime is one of the antibiotics that taken during pregnancy can be without harming the child or the mother. In the first three months, the antibiotic should only be taken strict prescription by a doctor be taken as the risk of damage is highest here.

The Standard dosage of cefuroxime is 250-500 mg twice a day for a period of five to ten days. The dosage is adjusted depending on the severity of the infection and the affected organ system, so no general information can be given here. A minor infection of the upper respiratory tract is usually treated with a dose of two times 250 mg daily, whereas pneumonia, for example, may require a dose of two times 500 mg daily. Uncomplicated urinary tract infections in women are treated with a lower dose of 125 mg twice a day. The Dosage of the drug but it is always a individual decision and depends on the type of infection and the severity of the disease. Furthermore, a dose adjustment is necessary in the event of impaired renal function.

Side effects

Cefuroxime whether administered orally or venously is deemed to be well tolerated antibiotic.
Side effects occur especially when high doses Cefuroxime be taken. Typical for Cefuroxime-Axetil are Diarrheathat occur due to a disorder of the intestinal flora. It can also stomach pain, nausea, Vomit and dizziness occur. The side effects can often be reduced by taking with or after eating. Another advantage of being absorbed while eating is that cefuroxime is better absorbed into the blood and therefore more effective.

Venous administered Cefuroxime can also Disorders of the gastrointestinal tract trigger (nausea, Vomit, Diarrhea). Before taking or administering cefuroxime, it is important to check whether a Penicillin allergy consists. In about 5% of cases, people with such an allergy also have an allergic reaction to cefuroxime. This can become partially strong Skin changes With Redness and Blistering or lead to painful inflammation of the blood vessels.

Please also read our article on this Antibiotic side effects

diarrhea

Side effects in the form of Discomfort of the gastrointestinal tract usually come in therapy with cefuroxime Rare in front. But one should be under diarrhea suffer is this to inform the attending physician immediately. Diarrhea can cause one significant loss of fluid lead and through it Cause complications. This must be prevented, especially during pregnancy. If you have diarrhea, you can choose another antibiotic if necessary.