Tetryzoline
definition
Tetryzoline is also known as tetrahydrozoline and is used in various medical fields.
Tetryzoline is a drug that has a so-called effect in its effect alpha adrenergic agonist, also known as sympathomimetics (see: sympathetic nervous system) corresponds to.
The main form of administration of the drug are primarily eye drops and nasal drops. Chemically, tetryzoline corresponds to one Phenylethyl derivative.
effect
Tetryzoline binds to receptors of the sympathetic nervous system (Part of vegetative nervous system, see: sympathetic nervous system) and activate it.
Since tetryzoline is mostly only used locally in the form of eye drops, nasal drops or sprays, it only works at the point where it can attach to the receptors.
As eye drop tie it up alpha adrenergic receptors and causes a general decongestant and soothing effect. In the form of eye drops, tetryzoline is used to treat symptomatic rather than causal Conjunctivitis or irritation applied.
After the eye drops have been put into the conjunctival sac, there is relatively quickly a reduced burning sensation in the eye, a reduced reddening of the conjunctiva and a reduced flow of tears. It is important to note that bacterial infections of the conjunctiva (purulent conjunctivitis) usually cannot be adequately treated with tetryzoline, as the pathogen can still remain in the eye despite treatment.
The second major area of application for tetryzoline is Nasal drops and Nasal sprays. Here, too, the drug binds to receptors, this time in the nasal mucosa.
The bond leads to a Activation of the sympathetic system and a decongestant effect on the nasal mucosa.
The main area of application is Cold with runny nose and swollen nasal mucous membranes, as well as the allergic rhinitiswhich can be triggered seasonally by pollen count.
Side effects
Generally will Tetryzoline well tolerated. Like all medications, there are also undesirable effects that you should be aware of before taking the medication. The relatively common side effects include local irritation.
When tetryzoline is taken in the form of eye drops, it may cause a burning sensation, reddening and increased tearing. Usually a side effect occurs after the first application.
Sometimes the side effects can lead to blurred or cloudy vision.
As a nasal spray or nasal drops, local irritation of the nasal mucosa can also occur. This would lead to itching or burning of the nose and possibly also to increased running of the nose and possibly also to sneezing attacks.
In some rare cases, tetryzoline has also been used general reactions of the body reports. To be mentioned here Dizziness, malaise, nausea and vomiting.
If side effects of tetryzoline occur, the drug should be discontinued immediately and exchanged for another drug.
Tetryzoline eye drops
As an eye drop, tetryzoline is the most widely used today. As a so-called Sympathomimetic it leads to a contraction of the vessels via receptor binding to the conjunctiva and thus to a swelling of the corresponding eye segment.
It occurs in ophthalmology especially when symptomatic Treatment of conjunctivitis for use. Even after conjunctival irritation, e.g. by Dust or smoke it can successfully provide symptom relief.
A drop of the drug should be placed in the affected eye 2-3 times a day. For this, the lower eyelid should be pulled down with the eye looking up and the drop should be placed in the conjunctival sac. Then the eye should be closed briefly.
As a rule, Tetryzoline eye drops are well tolerated.
But it can also happen that local irritation of the conjunctiva or the eyelids occurs. Sometimes itching or burning, as well as increased tearing, have been observed with tetryzoline eye drops.
Sometimes it can be temporary Dilatation of the pupil come, which in turn leads to indistinct vision.
Dilated pupils should return to normal within a few hours, otherwise you should see an ophthalmologist.
The application of the eye drops should not be carried out over a longer period of time without an appropriate diagnosis. If there is no improvement with the use of tetryzoline, the possible cause of the symptoms must be investigated.
Overdoses should be reported to a doctor immediatelybecause of an increased intake of tetryzoline Cardiac arrhythmias and general reactions can occur.
Even if tetryzoline eye drops are taken together with other medication, the relevant information leaflet should be observed as it increases Interactions between multiple drugs can come.
Tetryzoline eye drops require a pharmacy, but not a prescription. Read the package insert carefully before use.
Tetryzoline hydrochloride
The active ingredient tetryzoline is also used as a chemical combination with Hydrochloride processed and used. As tetryzoline hydrochloride, it has the same effect as tetryzoline, but differs in its chemical structure. In combination with hydrochloride, tetryzoline is mainly used in ophthalmology as eye drop used.
Hydrochloride is used in many drug preparations to positively change the water solubility of the drug. In most cases the effect can be accelerated somewhat.
When added to the eye drops, hydrochloride is said to accelerate the effect of tetryzoline.
pregnancy and breast feeding period
During pregnancy, eye drops and nasal drops containing tetryzoline are used not recommended.
The main reasons are the systemic ones Side effectssuch as cardiac arrhythmias and high blood pressure crises that can arise when taking the drug. The same applies to breastfeeding.
Should a pregnant woman suffer from conjunctivitis, should after consultation with a doctor antibiotic eye drops are more likely to be taken, which are not only better researched during pregnancy, but also have fewer side effects.
