Cocaine is rarely used as a doping agent. Cocaine is in the leaves of South American Coca bushes and is often used in Bolivia and Peru by the locals to defer the symptoms of fatigue. Cocaine is a alkaloid and is extracted from the active components of the coca bush. In 1750 the first coca bushes came to Europe from the South American countries. The consumption of approx. 0.05 grams leads to a euphoric reaction with an increased urge to be active. The reactions, however, were no different from the natural euphoria of humans. Until the early 19th century, Coca Cola contained 250 milligrams of cocaine.
Cocaine inhibits the reflux of the Noradrenaline in the synaptic cleft at the sympathetic nerve endings. This increases the concentration of noradrenaline at the receptor. Increased arousal, increase in Heart rate and vasoconstriction are the consequences. If the dosage is too high, there is a risk of muscle cramps and even respiratory paralysis. There is also a considerable addictive potential.
cocaine can be consumed in a wide variety of ways. It can be taken or smoked both orally, intranasally, and intravenously. Smoked cocaine has a stronger effect and takes just a few seconds. In some South American countries, the coca leaves are traditionally cooked in tea as a health-promoting effect. The import of coca tea in Germany is still illegal.
The taking of cocaine leads to a narrowing of the vessels with the consequence of High blood pressure, Increase in heart rate and irregularities in breathing rhythm. Cardiac arrhythmias up to Heart attack can be possible consequences. The use of cocaine leads to sleep disorders, disturbed feelings of hunger and thirst, and anxiety. Follow the sleep disorders are Hallucinations and disorientation.
After the euphoric effect it comes to a depressed mood which leads to a further urge to consume. A life-threatening dose for a cold is around 1.2 to 1.4 grams. Intravenously, the threat to life is already 0.7-0.8 grams.
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