Metformin for Polycystic Ovary Syndrome

Polycystic Ovary Syndrome (PCO)

The polycystic ovary syndrome is an abbreviation for polycystic ovary syndrome. It is a metabolic disease that affects women who are of sexually mature age. It is very common and has some sequelae, such as infertility or hyperandrogenism.The exact causes for the development of the syndrome are still largely unclear, but it is suspected that it can be genetic, but it is also noticeable that overweight women are often affected. Even though it happens so often, it is still often diagnosed very late. Many of the women affected have too many male hormones in their blood and this expresses typical symptoms such as male hair growth, irregular cycle, blemishes, hair loss, cysts in the ovaries (Ovaries) and a very serious symptom: unfulfilled desire to have children. The latter symptom is often the reason why this disease is discovered in the first place. The polycystic ovary syndrome is diagnosed by ultrasound and a hormonal status as well as by a thorough examination and anamnesis. It is very important to check whether there is insulin resistance, as this is a common cause of PCO syndrome. The syndrome can also have a few other consequences: These are, for example, mental disorders, increased miscarriages, social isolation, diabetes mellitus type 2 and cardiovascular diseases. If you want to have children, you can help with various medications such as hormones, a change in diet is also inevitable and overweight women need to lose weight. Metformin is a drug that works very well for both overweight and slim women. It is given when the metabolic syndrome is paired with insulin resistance.

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dosage

The dosage from Metformin cannot be established in general for all patients. There are the Film-coated tablets in 500mg, 850mg and 1000mg strength. A oral form of the drug is also available. The following applies to this 100mg in 1 ml. Depending on Strength of the disease and also how much is tolerated and the Side effects stop taking the drug. The dosage can 1 to 3 times during the day be and always be with meals. Often times will started with a weaker medicine and then slowly increased. It is just as possible that you first directly a high dose there and this then reduced when the body cannot tolerate it.

Alcohol consumption and metformin

At a Therapy with metformin becomes Recommended in all cases to refrain from alcohol, as mostly the Effect of alcohol can increase significantly. Often they are Effects of the drinks much felt earlier - Affected tolerate significantly less alcohol and are drunk much earlier and there is the Risk of alcohol poisoning, because the limit is exceeded quickly, or you quickly overlook your limits. Still it is not prohibited in principleTo drink alcohol. One should first talk to your doctor about it and be aware that you can can drink much less and must be careful. Excessive alcohol consumption Unfortunately, it can not only make patients drunk faster, but also lead to a Lactic acidosis comes. He can also, especially if the patients are still have diabetes to a rapid hypoglycaemia to lead.

A Lactic acidosis is a illnesswhich definitely not harmless can be. The blood and the tissue show you decreased pH on, that is, the Body turned sour is there yourself too much lactate located in it. There are multiple causes for lactic acidosis. For one thing, you can Kidney damage lead to the PH value degraded and accumulated too much lactate. Also can excessive alcohol consumption and a Liver damage lead to it. The Taking medication of certain drugs, including metformin, is also a Risk factor. There is more lactatebecause the Converts pyruvate to lactate in the absence of oxygen and the Liver function insufficient is. It can also increase if the Citric acid cycle disturbed is.

The therapy is individually, depending on which one root cause underlying. Treating the symptoms is not enough; it is important, always the Treat the cause. The disease manifests itself through various symptoms how nausea and Vomit, stomach pain, fatigue, Circulatory problems and Loss of appetite. A Hypoglycaemia is also expressed through many symptoms how Racing heart, paleness, Sweats, Cravings, dilated pupils and Tremble the whole body. Blood sugar drops always further downso make yourself slow Motor disorders, Speech disorders, Difficulty concentrating, Seizures, a headache and also Impaired consciousness noticeable. Of the Blood sugar is important for the bodyso that each cell can work sufficiently and the power supply is ensured.

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Pregnancy and metformin

in the Relation to PCO has been found in previous studies and observations that the Abortion rate significantly reduced had if pregnant women the drug Metformin during the first trimester continued had. In contrast, there was a comparative one high rate of miscarriageswhen pregnant not treated with metformin were, or that Drug discontinued too early has been. There is generally one in women who suffer from polycystic ovary syndrome and have diabetes significant improvement in pregnancy, even if they Metformin The whole time take in. It absence but still great studieswhich examine more closely to what extent the drug actually has a better effect. But it should Early abortions and the Pregnancy sugar reduce. The best information however, the attending physician because he knows the exact circumstances of the respective woman best and is always up to date with studies and new findings on the individual drugs and the respective side effects.

Lose weight with metformin

A big risk for the Development of a PCO and also for that Development of diabetes mellitus 2 is this Obesity. It has been found that nearly 70% of women with PCO weigh significantly too much. So it is inevitable to lose weight, if the Illness treated should be or even one want to get pregnant. When in overweight adults all diets fail and they in addition already have diabetes, then it is inevitable one Therapy with metformin to start. The Medicine significantly reduces complicationswhich would be associated with diabetes. There are hardly any drugs that help as well as metformin. But you can take the medicine Do not think of metformin as a weight loss pillbut rather than a Body sugar reducing agent. Additionally To take metformin, it is essential for the patient to lose weight and the To fundamentally change your diet. You can go here Help from the attending physician, but also with one Nutritionist who can then respond individually to the individual needs and also knows all other important factors such as age and additional illnesses.

Side effects of metformin

The side effects of metformin are unfortunately extensive. Combinations with other groups of active substances such as Be aware of alcohol. We have therefore published a completely separate page on the subject of "Metformin Side Effects".

Read extensive information on the side effects under our topic: Side effects of metformin

Further information

• Metformin
• diabetes
• Diabetes mellitus
• Type 1 diabetes mellitus
• Type 2 diabetes mellitus
• Diabetes mellitus symptoms
• Diet in Diabetes
• Therapy diabetes
• Drugs diabetes mellitus
• Table of contents Diabetes mellitus

Further subjects that might interest you:

• Actraphane
• Aplphaglucosidase inhibitors
• Amaryl
• Glinide
• Glucophage
• Lantus®
• Metformin
• Sulfonylurea
• insulin

All information from the field of medication can also be found under Medicines A-Z!

Exclusion of liability / disclaimer

We would like to point out that medication must never be discontinued, applied or changed independently without consulting your doctor.
Please note that we cannot claim that our texts are complete or correct. The information may be out of date due to current developments.