Pyruvate arises in the human body during sporting activity and every kind of physical stress in which the muscles work. Since pyruvate is also involved in cell respiration and other important biological processes in our body, it can be called important biological molecule describe. In addition to the term pyruvate, the synonym “salt of pyruvic acid” is also used.

Under pyruvate is a Molecule with three carbon atoms understood, which also has two so-called functional groups. This group are atoms that are responsible for the characteristics of the molecule. The two functional groups are called ketone and carboxyl groups.

In the body, pyruvate arises from the breakdown of carbohydrates or the breakdown into its individual parts and the subsequent introduction into the citric acid cycle, which is used to generate energy.
The body can also obtain energy directly from pyruvate and thus skip a step in energy production. Pyruvate also has the advantage that it cannot be easily converted into fat.

Effect as a supplement

in the Weight training and endurance sports is also called pyruvate Food supplements used and should especially the Promote muscle building as well as the endurance influence positively.

Pyruvate is said to increase the glycogen level in the muscle cells and thereby Increase strength and endurance and at the same time the Decrease appetite. Pyruvate is also said to have the Accelerate energy delivery, and to make sure that more fat and fewer carbohydrates are burned in the muscle cells. In addition, pyruvate ensures that Glucose and proteins get into muscle cells faster and thereby also the muscle building is positively influenced.

So far, many have Studies on the effects of pyruvate carried out as a supplement. It could be proven that pyruvate itself has a positive effect on athletic performance and also at Losing weight helps. The energy supply is optimized and so it can be significant when taking pyruvate as a supplement Increases in muscular endurance come.

A study could show that in a Supplement with 25 grams of pyruvate daily the endurance of the upper and lower extremities could be increased by up to 20 percent. Pyruvate takes care of you higher transport of glucose from the blood to muscle cells and thus ensures the supply of energy for a longer period of time.
This effect also affects the athlete's endurance performance. In athletes who want to lose weight, pyruvate was also able to achieve significant success and improved Fat burning lead to weight loss.

In conjunction with a low energy diet can the Pyruvate supplementation to a Weight loss to lead. This could be shown in a study in which 20 grams of pyruvate were supplemented daily for three weeks. The weight loss is characterized to a large extent by a loss of fat mass.
The exact mechanism behind this has not yet been adequately investigated. One guess is that pyruvate works for one Increase in energy demand leads. However, since there are fewer carbohydrates in the body due to the low-energy diet, the body relies on the burning of fat as an energy source and thus reduces body fat. Also a better body feeling was attributed to pyruvate by study participants who changed after pyruvate supplementation better and fitter felt.

However, there are also studies that disagree on the positive effects of pyruvate as a dietary supplement, as these studies often refer to overweight people who have so far been little or no physical activity.

Side effects of pyruvate

In contrast to the exact mode of action of pyruvate as Food supplements side effects are undisputed.
When taking pyruvate as capsules, powder or tablets you can stomach problems occur. You can do this stomach pain, Stomach cramps and Digestive problems belong. Besides, it can too soft stool and possibly also to diarrhea come.


The human body can Make pyruvate yourself and is therefore not necessarily dependent on supplementation. However, the amount of pyruvate that the body can synthesize is relatively small. In order to always have enough pyruvate in the body, between two to five grams of pyruvate per day, taken with meals, completely off. athlete have a higher energy requirements and therefore also need more pyruvate to achieve positive effects.

As studies have shown, the daily dosages are at least 20 grams per day quite high. Since pyruvate is also not a cheap food supplement, supplementation with this substance can quickly cost several euros per day. If the doses are lower than 20 grams, the effects of the pyruvate can be observed to be weaker and weaker. If you really want to benefit from supplementation with pyruvate, you should take at least 20 grams per day in the form of capsules, tablets or powder.

The danger both high amounts is then, however, that the unwanted side effects as, stomach cramps, stomach pain, diarrhea, loose stools and malaise may be increased.
Becomes Pyruvate too high a dose has it no additional effectbecause the body can only absorb a certain amount of pyruvate at a time. This is due to the low rate of absorption of pyruvate. The excess pyruvate is then simply excreted through the stool.

Other food supplements

More information about Nutritional supplements can be found at:

  • amino acids
  • BCAA
  • CLA
  • Glutamine
  • HMB
  • carbohydrates
  • L-carnitine
  • protein
  • Ribose
  • Weight gainer
  • Tribulus Terrestris
  • Creatine