Volon A
synonym
Triamcinolone acetonide
introduction
Volon® A is a drug that belongs to the group of glucocorticoids.
Glucocorticoids have the property of counteracting inflammation and allergies and reducing the body's immune response.
Due to these three properties of Volon® A, it can be used for a wide variety of diseases. The application ranges from inflammatory skin diseases to rheumatic diseases and allergic reactions.
However, Volon® A does not eliminate the cause of the symptoms, it only improves the symptoms.
Volon® A is a prescription drug.
Mechanism of action
As a glucocorticoid, Volon® A attacks receptors in protein synthesis, so that a reduced production of proteins takes place, which are required for inflammatory reactions and allergic reactions.
If these proteins are missing, the operational capability of the immune system is reduced.
In addition, Volon® A has an inhibiting effect on cell proliferation.
Volon® A has one on the bronchial mucosa decongestant effect, and causes the Expansion of the bronchi.
application areas
Due to its versatile mode of action, Volon® A can be used for many complaints.
It is particularly often used in:
- Skin disorders how psoriasis (Psoriasis), Eczema (Itching), radiation erythema, erythema nodosum
- Rheumatic diseases again Rheumatoid arthritis or the acute one Rheumatic fever
- Allergic reactions like allergic rhinitis, allergic conjunctivitis and the septic shock. Also if you have severe allergic reactions Volon® A can be used on insect bites.
- Lung disease such as (chronic) bronchitis, COPD, asthma or at Sarcoid
- Diseases of the stomach and intestines how Crohn's disease
- Kidney disease like nephrotic syndrome.
Dosage form and dosages
Volon® A is available as a tablet, ointment or syringe.
Which form is most suitable depends on the disease that is to be treated with Volon® A.
The daily dose also varies depending on the area of application 10-280 mg / day.
For long-term therapy, the Dosage kept low if possible to reduce the side effects of long-term use.
Side effects
Side effects are characteristic of Volon® A in long-term use and at high dosage.
A typical consequence of long-term high dosing is this Development of a Cushing syndrome which, among other things, lead to weight gain, high blood pressure, Osteoporosis and hormonal imbalances.
Since Volon® A suppresses the immune system, it leads to a Susceptibility to infection. On the one hand, this applies to new infections with pathogens, but also existing diseases that the body had under control can reappear.
The drug also affects the patient when taken for a long time Bone metabolism out so that it becomes a osteoporosis or worsen an existing osteoporosis.
Also one Effect on the central nervous system is possible. Here you can sleep disorders, Listlessness and mental illness occur.
There is already a non-symptomatic one Diabetes mellitus, it can lead to symptoms when taking Volon® A and must be treated accordingly immediately.
As the drug inhibits cell division, kick in children stunted growth on that after the end of therapy in most cases are declining again.
Contraindications
At a immunodeficiency The intake of Volon® A is not recommended, as it additionally suppresses the immune system.
At severe infections Volon® A cannot be used either.
At Damage to the gastrointestinal mucosa, severe osteoporosis and mental illness The advantages and disadvantages of therapy with Volon® A must be weighed.
Drug interactions
Volon® A inhibits the effect of blood clotting agents and Diabetes medicationtaken in tablet form.
When combining Volon® A with nonsteroidal rheumatoid drugs the risk of gastrointestinal bleeding increases significantly, so this combination should be avoided.
Barbiturates, rifampicin and Phenytoin reduce the effect of Volon® A.
Use during pregnancy and breastfeeding
Volon® A is allowed during pregnancy and breastfeeding Not used, since it crosses the placenta and its inhibitory effect on cell proliferation Stunted growth in the child.
