Lymphatic Cancer Prognosis

introduction

Lymph gland cancer is a malignant degeneration of the cells of the lymph system, including the lymph fluid and the lymph nodes.

Lymphatic cancer is divided into two subgroups:

1. Hodgkin's lymphoma and
2. Non-Hodgkin lymphoma

Hodgkin's lymphoma occurs at a rate of 3 new cases per 100,000 people. Non-Hodgkin lymphoma is more common with a frequency of 12 per 100,000 population. Today there are a number of treatment strategies that can be composed of chemotherapy and radiation. An individual therapy adjustment is necessary for each patient. So play factors like:

  • Age
  • other comorbidities
  • Stage of the disease and
  • Formation of metastases

plays an important role in deciding how to treat.

Life expectancy in lymphatic cancer

It is not easy to say how long the life expectancy with lymph gland cancer is, as a large number of factors play a role in determining an expected survival time.
First of all, it should be noted whether a patient is on a Hodgkin or a non-Hodgkin lymph gland cancer is sick.
Then there will be Age of the patient and Comorbiditiesthat were already present in the patient before the onset of cancer is taken into account.
It is also important how well the patient responds to an initiated treatment. If the treatment has to be stopped early because of side effects or poor general condition, life expectancy will also deteriorate.
With successful treatment of the so-called first-line therapy, life expectancy improves, but decreases in the event of a relapse (Relapse) and a necessary secondary treatment. It is also important to note that the prognosis of the cancer may be good in some cases, but the long-term damage of the necessary treatment contrasts with a long survival time.

A so-called staging is carried out to determine the prognosis. This is understood to mean several diagnostic procedures that are intended to show how far the cancer has progressed is. Based on the staging, the cancer can then be assigned to a stage. The staging is therefore decisive for the type and duration of the therapy initiated and is carried out first for every cancer patient.

Also read: Lymphoma prognosis

With a Hodgkin lymphoma one differentiates limited stageswhere there is still none Metastasis has come. Just a lymph node station is affected and the patient does not suffer from the so-called B symptoms (Night sweats, fever, and weight loss). In the limited stages, the patients have a good prognosis. Over 90% of the patients survive the next 5 years.

With the so-called Intermediate stage (a stage that is between the limited and advanced stage in severity) it is just under 90% and at that advanced stage about 88% of the patients who are still alive after 5 years.

At the Non-Hodgkin lymphoma, of which there are still numerous subgroups, the mean survival rate is 10 years, including disease courses with survival rates between 2 and 20 years. Decisive in the length of the survival rate is next to that Time of diagnosis and the chosen type of therapy also the complication rate of the therapy carried out.

When determining the probability of survival, the so-called flip index emerged. It includes risk factors and probabilities of a recurrence of the lymph gland cancer.
So patients would have a 10 year survival rate of 70% if they no or only one risk factor would have. At 2 risk factors they would have a survival probability of almost 50% and with more than 2 Risk factors the probability of the patient being still alive after 10 years would be 30%. The more risk factors there are, the higher the risk of recurrence, i.e. the risk that the disease will return with treatment.

Chances of recovery

Chemotherapy is also used to treat cancer of the lymph gland.

The Hodgkin lymphoma has one compared to other cancers good chance of recovery. The decisive factor here is, among other things, the time at which the disease was diagnosed, how far the disease has progressed and what condition the patient is in and how to accept therapy.
With an early diagnosis, still not advanced stage of the disease and the patient is in good health, the chance of recovery is 95%. Nonetheless, the therapies used can have significant side effects, which will then also occur in the distant future Late damage being able to lead.
The development of other cancers is also possible through the chemotherapy and / or radiation.
At advanced disease The chances of recovery temporarily drop to below 10%. In the vast majority of cases, treatment is started immediately after the diagnosis. This consists of one Combination of chemotherapy and radiation. In very few cases the disease has progressed so far by the time the diagnosis is made that the start of treatment has to be dispensed with completely. Sometimes, however, it can happen that the treatment has to be discontinued in the absence of the expected improvement or in the case of intolerance to the medication and / or radiation in order not to weaken the body more than necessary.

More information can be found here: Lymphatic Cancer Cure Chances

Chances of recovery in children

Every year around 500,000 people in Germany develop cancer, around 1800 of them are under 14 years old. Around 150 children in Germany develop Hodgkin's disease every year.
Include in children Blood and lymph gland cancers are among the cancers that are most effectively treated can.If the diagnosis is made early, treatment is started very quickly, which can sometimes last up to a year. As a rule, children do not yet have any underlying diseases that would complicate the treatment of lymph gland cancer and drastically reduce the chances of recovery. Presumably the still very intact tissue and the well-developed defenses of the young patients are responsible for that Therapies very well tolerated be that Side effects occur less often than in adults and that the disease can be treated more successfully as a result.
Between 80 and 95% of all children with lymph gland cancer are cured, although long-term side effects from the treatment, which can occur 20-30 years later, are not counted. Cancer recurs very often after a long period of time after primary treatment.

Chances of recovery from relapse

If the disease recurs after an initially successful treatment of a lymph gland cancer, one speaks of a Relapse. If a relapse occurs after primary treatment, the chances of recovery unfortunately decrease. On the one hand, this is due to the fact that Recurrent diseases are usually much more aggressive are considered to be the primary disease, on the other hand, that the available treatment options are no longer as effective and are no longer readily accepted by the body. On the other hand, some treatment options can only be used to a limited extent or not at all in the case of a relapsing illness (for example radiation).

One must also take into account that the body can be very weakened by the initial treatment and no longer has the defenses to survive a new treatment so easily. In most cases, second-line therapy is started as soon as the diagnosis of relapse has been made, but in some cases this treatment has to be discontinued due to excessive side effects. The desired therapeutic success is often not achieved after the start of the second-line treatment, which becomes clear, for example, in the progression of the disease under therapy. In this case the treatment would be stopped.