AMPHETAMINES / WAKE AMINES

introduction

Amphetamine and methamphetamine belong to the group of wake-up amines. The ingestion of wake-up amines is considered doping and improves coordination skills during physical activity. The wake-up amines stimulate the central nervous system (CNS). This leads to an improvement in the interaction between the CNS and muscles. Weckamines have a performance-enhancing effect, especially when you are tired. The fatigue-related decline in performance can thus be counteracted by alarm clocks. As a result, wake-up amines are used in endurance sports.

effect

The effect of the Weckamines results from the chemical relationship to adrenaline and Norepinephrine. This body's own Hormones are transmitter substances of the sympathetic nervous system in the peripheral nerve endings. The hormones adrenaline and noradrenaline are in the Adrenal gland formed and released from there directly into the blood.

During exercise, the activity of the sympathetic system increases and adrenaline and noradrenaline are released from the stores into the synaptic cleft. The hormones diffuse through the synaptic gap to the receptors of the successful organ, where they trigger the following effects:

Increase in heart rate

Narrowing of the vessels

Stimulating effect with improved coordination

After the effects have subsided, 90% of the hormones are returned to the Granules stored, and about 10% is broken down by hormones. When mentally aroused, norepinephrine is released mainly from the peripheral nerves and adrenaline from the adrenal gland.

Why is maximum performance possible under anxiety conditions:

In the situation of fear there is a release of adrenaline. This gets into the liver and activates the breakdown of glycogen to glucose. This prevents the glucose concentration in the blood from falling, and athletic performance can be sustained for longer. The two main representatives of the wake-up amines are amphetamine and Methamphetamine. The effect of the wake-up amines can with Norepinephrine be compared. Weckamines also cause noradrenaline to be released and stored back. There is an increase in heart rate and high blood pressure.

By the happening of Blood-brain barrier The wake-up amines have a stimulating effect and thus improve the Movement coordination. Onset of signs of fatigue are not consciously perceived, so athletic performance is possible over a longer period of time. However, wake-up amines do not increase maximum performance, only the duration.

Side effects

Wake-up amines cause a loss of appetite with increased physical activity. One consequence is that Weight reduction even with a constant energy supply. The release of energy leads to increased heat production, which leads to a feeling of heat.
A daily dose of more than 3-6 mg leads to an increase in the resting heart rate, high blood pressure and even circulatory shock.

As a result of the stimulation, poor concentration, insomnia and increased potential for aggression can arise as side effects. With continued use of Amphetamines and methamphetamines lead to typical addictive behavior with associated withdrawal symptoms. Due to the vasoconstricting effect, the substances used to decongest the swelling of the mucous membrane (nasal drops). Due to the bronchodilator effect, the substances are considered to be asthma drugs.