Vomex®

Synonyms in a broader sense

Dimenhydrinate, H1 receptor blocker, antihistamine, antiemetic

Other trade names: Vomacur, Reisefit, Reiseabletten, Reisegold, Arlevert

introduction

Vomex® is the trade name of a drug with the active ingredient dimenhydrinate.

Dimenhydrinate is a combination of the two individual components diphenhydramine and 8-chlorotheophylline.
It is mainly used for nausea and vomiting, which is where it got its name from (to vomit, English = to vomit). It can also be used as a sedative. The actual effect is based on the diphenhydramine; 8-chlorotheophyllin serves to reduce the tiredness caused by diphenhydramine and has a similar effect to caffeine.

Read more about this under Anti-Nausea Medication

Dosage form

Dimenhydrinate (Vomex®) is available in various formulations and dosages:

• dragee
• syrup
• Solution for spraying as an alternative for strong gagging
• Tablets: possible to take with or without a meal. With strong nausea and Vomit possibly difficult.
• Chewable tablets: Often with travel sickness applied.
• Suppositories (Latin suppository): for use in the rectum. The suppository must be inserted into the anus. A particular advantage is that it is easier to use in children and, as an alternative, in the case of strong gagging and vomiting, also in adults.

dosage

Suppositories:
- Infants 8-15kg: 1 children's suppository (40mg each) per day
- Children 15-25kg: up to 2 children's suppositories (40mg each) per day
- School children> 25kg: up to 3 children's suppositories (40mg each) per day
- The stronger children's suppository forte (70mg) can be given from 15kg
- Adolescents from 14 years and adults: 1-2 suppositories (150 mg) per day
Dragees (50mg):
- Children 6-14 years: 1 coated tablet 1-3 times per day
- Adults and adolescents aged 14 and over can take 1-2 coated tablets 1-4 times a day
Retard capsules (150mg):
These capsules have the advantage that they only work with a delay and a little longer. As a result, they are not so suitable for acute nausea. From the age of 14, 1 capsule can be taken 1-2 times a day.

application

Most often, Vomex® is used for prevention at Travel sickness (for example, when you feel sick when driving a car). It should be there Not from driver be taken by yourself, as Vomex® makes you tired (sedative effect).
Dimenhydrinate is also found as an active ingredient in numerous other “travel tablets”.
Vomex® can also be used for other types of nausea and at Vomit are given. For the prevention and therapy of nausea chemotherapy should not be given alone as it will not have sufficient effect in this situation.
Also at dizziness it can provide relief from nausea and malaise in some cases.

Side effects

So-called undesirable effects occur antihistaminergic Effects.
Vomex® has an overall dampening effect on the higher functions of the brain, which can also lead to a general slowdown in the ability to react. Due to drowsiness and decreased responsiveness should no vehicles (Cars!) And dangerous machines are used.
The appetite may increase.
There are also so-called anticholinergic Effects. These include Dry mouth, Racing heart, dilated pupils and Visual disturbances, Problems urinating.
Also Constipation or Diarrhea are possible. These side effects are more common in the elderly.
Furthermore, the Blood pressure come. Especially in patients with a so-called "Long QT Syndrome" can it to Cardiac arrhythmias come. Therefore, people with such a disease should refrain from taking it.

In the event of overdoses, Vomex® hallucinogen Act.

By chewing the coated tablets it can become a short term deafness come in the mouth.

In children it can become a paradoxical excitement with overactivity come (paradoxical because Vomex® tends to promote sleep in adults).

Drug interactions

When taking additional medication that one Extension of the QT time affect the heart (see package insert) it can lead to Cardiac arrhythmias come. Therefore, the compatibility with other drugs should be checked by a doctor or pharmacist.
Together with alcohol, Antidepressants, Neuroleptics and strong (containing opioids) Painkillers and sleeping pills increase the dampening and sleep-promoting effect.

Use during pregnancy and breastfeeding

No harm is to be expected for the unborn child. In the last Trimester (from the 7th month of pregnancy) Vomex® should be avoided because it labor-inducing works.
In the Lactation it should not be ingested.

Contraindications

Vomex® should not be taken if:
- allergy/ Hypersensitivity to antihistamines
- in acute Asthma attack
- Angle-closure glaucoma
- Phaeochromocytoma
- at benign prostatic hyperplasia (benign enlargement of the prostate) with residual urine
- Seizures

Particular caution also applies to Cardiac arrhythmias, Liver dysfunction, long QT syndrome, as well as chronic asthma and at Constrictions of the gastric outlet (Pyloric stenosis).