Aknefug®
General
Aknefug® refers to a group of drugs that consists of three different drugs (erythromycin, isotretinoin and benzoyl peroxide) and is used to treat the skin disease acne.
There is also a drug known under the trade name Aknefuq®, which is mainly sold for local use, in the form of ointments or pastes.
Aknefug-EL®
Aknefug-EL® is a Solution for use on the skin, this is used for inflammatory forms of acne.
The antibiotic Erythromycin fights various bacteria that can be involved in the development of inflammatory acne.
It belongs to the Group of narrow-spectrum antibiotics, this means that it can only act against a selected group of pathogens and has no effect on other bacteria.
The spectrum of action, i.e. the range of bacteria that react to erythromycin, is the same as that of Penicillins comparable.
The advantage of erythromycin is that it is straight in patients with penicillin hypersensitivity (allergy) is a good treatment alternative.
Basically it can not only be used for acne therapy, but mainly for treating one Otitis media, one Sinus infection and various respiratory infections are used.
In general, this antibiotic is very well tolerated, but some patients report it after systemic ingestion from Side effects how mild Gastrointestinal complaints, Tinnitus and or temporary hearing impairment.
The following side effects can be mentioned as a solution on the skin: Contact allergy, Dehydration, Redness, Burn, Itching of the skin.
Aknefug-ISO®
Isotretinoin is a derivative of retinoic acid, thus similar to vitamin A, and has been approved for the treatment of acne since 1982.
This Aknefuq®- drug reduces the size of the sebum glands the skin, from which a normalization of the rate of production of the glands follows. The inflammatory acne can heal more effectively with isotretinoin administration Relapse (relapse) after discontinuation the drug is however No rarity. Re-therapy is necessary in around 60% of those treated.
Since isotretinoin therapy is a wide range of side effects is the use of this drug only in serious cases of illness to recommend.
The treated patients report very frequently after taking small sores of the skin, Flaking skin, Rashes and severe itching.
It also occurs in many cases Epistaxis, Inflammation of the mucous membranes and even Hair loss on.
Oral administration of this drug (for example in tablet form) can Normal liver function disorders and fat metabolism occur. In very rare cases, the patients treated suffer one Inflammation of the liver (hepatitis) as a result of taking isotretinoin.
In addition, inflammations in the area of the eyelid margins and the conjunctiva develop very often, the affected patients suffer from it more and more Dryness and irritation of the eyes.
In extremely rare cases, develop under drug administration Visual disturbances in the form of ametropia, night blindness, corneal opacity and / or color blindness.
Due to the comparatively extensive side effects, the use of isotretinoin should be carefully considered.
This drug should not be used in patients who have a lipid metabolism disorder (hyperlipoproteinemia), skin disorders, or increased pressure in the eye.
Aknefug-OXID / -BP®
Benzyl peroxide is used for external application of acne, especially when Appearance of nodules and pus vesicles.
It has a peeling effect and thus prevents the (new) formation of blackheads. It also inhibits sebum production, which in turn Reduced fat content of the skin. The growth of acne bacteria is also inhibited, so inflammations subside quickly.
Since benzoyl peroxide belongs to the group of organic peroxides, it is able to "neutralize" free oxygen radicals and thus develop its antibacterial effect.
As Side effects are actually just Hypersensitivity reactions With Reddening of the skin, slight burning, Flaking of the skin to call. However, this has something to do with the mechanism of action of the product. The reactions should not become too strong and should not last too long. Pre-existing skin conditions such as dry skin or atopic eczema can increase the risk of these symptoms.
Intense solar radiation should be avoided during treatment. The preparation should not be used in case of hypersensitivity to peroxides. The contact with eyes, Eyelids, Lips, mucous membranes and irritated skin should be avoided
Aknefug®
That under the Trade name Aknefug® known drug can be used for mild to moderate acne.
Among other things, it contains the active ingredient Dibenzoyl peroxide (Benzyl peroxide) and therefore acts according to the mechanism described above.
The ointment should usually twice a day sparingly on damp skin and for about Work for two to three minutes. Then the preparation must be washed with warm water washed off thoroughly become.
In the case of skin reactions such as redness, flaking or feelings of tension, it is advisable to reduce the application to every two days.
After a few days, these side effects decrease in most cases and the application intervals can be slowly shortened.
