Thyronajod®
introduction
Thyronajod® is a preparation for the treatment of thyroid disorders, more precisely the treatment of an underactive thyroid (Hypothyroidism) or a goiter (goiter) without thyroid dysfunction.
The manufacturer is the company Sanofi-Aventis in Frankfurt am Main.
The thyroid is located in front of the windpipe on the human neck. Usually it is not visible or palpable.
A palpable enlargement of the thyroid gland is called goiter and often occurs in combination with dysfunction of the thyroid gland.
The hormone made by the thyroid gland is called thyroxine. Thyroxine generally stimulates and accelerates the metabolism in the body.
If the thyroid function is out of balance, either an underactive thyroid arises (Hypothyroidism, "Hypo" = "under") in which too little thyroxine is produced or an overfunction, which is then called Hyperthyroidism ("Hyper" = over) and in which too much thyroxine is produced.
Thyronajod® replaces the body's own thyroxine in the event of a thyroxine deficiency and is therefore used as the drug of choice for an underactive thyroid.
Since a goiter can also be caused by an iodine deficiency, the iodide contained in Thyronajod® can additionally support the thyroid, because it needs iodine to produce thyroxine and increases in size with a deficiency of iodine.
Read more on the subject below Iodine deficiency or Thyroid medication
What does Thyronajod® contain?
The active ingredients contained in Thyronajod® Levothyroxine Sodium (short: "L-Thyrox") and Potassium iodide both counteract the hypothyroidism.
Thyronajod® is in the strength of 50, 75, 100, 125, 150 micrograms Levothyroxine and 138.8 or 196.2 micrograms Potassium iodide available.
The included Levothyroxine replaces the body's own thyroxine, which is produced in a Hypothyroidism there is too little in the body.
iodine is essential for the formation of thyroid hormones, as it is an important component of thyroxine.
Thus, the thyroid contained in Thyronajod® can supply additional iodine if this e.g. owing to Iodine deficiency is enlarged or a hypofunction has developed.
dosage
Thyronajod® should always the Should be taken according to the instructions of the attending physician or pharmacist.
The treating doctor determines the daily dose.
Here it applies Interactions and other diseases of the person concerned to be included in the dosage instructions and to be taken into account when choosing the dose.
That is important morning intakethat always sober and at least half an hour before breakfast should be done. The tablet should be taken while taking not chewed and can be taken with a glass of water for easy transport.
Simultaneous consumption of coffee can delay absorption into the body.
If the person concerned has forgotten to take a dose, he must not take it up, but should continue taking it in the normal rhythm the next day.
The therapy time with Thyronajod® differs depending on the cause and in many cases lasts between six months and a year. During therapy should regularly checked thyroid levels in order to control the success of the therapy and, if necessary, to end the therapy or to adapt it to a changed thyroid function.
Can children take Thyronajod®?
Children under the age of 14 should no Thyronajod® take in. Since an underactive thyroid in children is usually caused by one Iodine deficiency arises, therapy with iodine alone is usually sufficient.
Can pregnant and breastfeeding women take Thyronajod®?
Affected one Hypothyroidism It is imperative that you continue taking Thyronajod® during pregnancy, as correct treatment is particularly important during this time.
The intake should be carried out under particularly intensive medical supervision during this time. So far, no negative effects of Thyronajod® on the unborn child have been proven.
Also in the Lactation According to previous knowledge, Thyronajod® can be taken without any concerns, as the amount of components of Thyronajod® that pass into breast milk is very small.
However, the daily dose of 200 micrograms iodine should be used both during pregnancy and breastfeeding not be exceeded and when taking other drugs containing iodine.
When should I not take thyron iodine?
Like all other drugs, it is also allowed Thyronajod® not to be used if one is allergic to Levothyroxine, Potassium iodide or one of the other ingredients of Thyronajod®.
This also applies particularly to previous reactions to iodinated contrast media or iodine-containing drugs such as Amiodarone against Cardiac arrhythmias to pay attention.
A few rare skin diseases that are triggered by iodine, such as a special form of vascular inflammation, should also lead to the avoidance of Thyronajod®.
Before taking Thyronajod® must be excluded that the thyroid gland so-called autonomous areas having. These areas produce uncontrolled thyroxine and the production rate would increase uncontrollably through the administration of additional Thyronajod®.
If there is a suspicion of a so-called autonomous area, this suspicion should be clarified by further examinations in order to be able to take Thyronajod® depending on the result.
Logically, Thyronajod® should not be taken if you have your own overproduction of thyroxine in the context of a Hyperthyroidism suffers.
Since the metabolism-increasing effect of Thyronajod® also affects the Cardiovascular system have to take Thyronajod® in diseases of the cardiovascular system such as Heart attack, one Coronary heart disease, Inflammation of the heart muscle (Myocarditis) or des Heart sac (Pericarditis) but also high blood pressure be carefully weighed, or these diseases are excluded before ingestion.
The reason for this is that an increased metabolism and a stimulation of the circulatory system are always associated with more work for this system. Parts of this system that have already been damaged can possibly fail due to this additional load and this can lead to life-threatening situations such as Heart attack, cardiac arrhythmia, heart failure or even high blood pressure crises come.
These diseases should be monitored closely while taking Thyronajod® regularly.
Further caution should be exercised in women past menopause. Here the dose should be chosen very carefully, as there is too much hormone osteoporosis can trigger or accelerate. Due to the metabolism-increasing effect of Thyronajod® there is a Acceleration of bone metabolism.
Side effects
Because Thyronajod® is the body's own hormone Thyroxine replaced, the side effects occur especially at the beginning Hyperthyroidism on.
In the course of the circulatory stimulation it can be too Palpitations from a heartbeat that is too fast (Tachycardia) up to insufficient supply of the entire heart with heart attack-typical chest pain, which then often radiates into the left arm. It can also Cardiac arrhythmias occur.
Furthermore, it can become one through the extreme stimulation of the metabolism in the entire body Feeling hot come that from excessive sweat can be accompanied.
Many of those who have been treated also complain Shaking hands (tremor) or about insomnia.
The gastrointestinal tract also reacts to the overactivation and those affected can undergo diarrhea Suffer.
If you notice one of these side effects, the dose should be checked by the doctor and reduced for a certain time if necessary.
The iodine also contained in Thyronajod® can lead to reactions such as Fever, rashes, itching, dry cough, diarrhea or headache by a Hypersensitivity to iodine come.
Again, a must Consult a doctorto optimize the intake of Thyronajod®.
What else should you watch out for?
Thyronajod® requires a prescription in Germany, that is, it may only be prescribed by a doctor and dispensed by the pharmacy.
The intake of Thyronajod® can interact with the intake of other medications. It is particularly important here anticoagulant drugs how Phenprocoumon (Marcumar) to pay attention to.
By changing the metabolism should also the effect of Blood sugar lowering drugs against diabetes mellitus, because the increased metabolism can weaken its effect and it can lead to high blood sugar in those affected.
In this case, the dose of the medication must be adjusted by the doctor for the duration of the therapy with Thyronajod®.
Furthermore, switching between different preparations for the treatment of hypothyroidism is only permitted under medical supervision, since the same ingredients can differ considerably in terms of their duration of action and the type of metabolism in the body.
For certain drugs, it is also important to keep a time interval of 4-5 hours so that the absorption from the intestine could otherwise influence each other.
These include drugs for Lowering blood lipids, some medicines for high levels of cholesterol in the blood (called Bile acid sequestrants) or Remedies for high blood potassium levels.
An intake interval of two hours is with aluminum-containing Heartburn preparations necessary.
The decisive factor for all of these preparations is their absorption in the intestine. Many drugs are absorbed into the intestines in the same way. If there are too many active ingredients in the intestine, they compete and it can no longer be guaranteed that all active ingredients will be adequately absorbed in the body.
Since the Interaction list Anyone affected should take other medication for a very long time Before taking L-thyroxine, always inform the doctor treating you of all medications without exceptionin order to avoid the interactions that should not be underestimated.
In addition to medication, there are also nutritional habits to consider. Affected people who eat particularly soy content may have to take a higher dose of Thyronajod®, as soy, similar to the drugs described above, has Reduce absorption from the intestine can.
